[CAS NO. 26543-89-5] Hinokinin

Name: Hinokinin
Brand: Arctom Scientific
SKU: AS102898

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PRODUCTS SPECIFICATIONS [26543-89-5]

Fulfillment

Catalog

AS102898

Brand

Arctom Scientific

CAS

26543-89-5

DESCRIPTION [26543-89-5]

Overview

MDL	-
Molecular Weight	354.35
Molecular Formula	C20H18O6
SMILES	O=C(OC1)[C@H](CC2=CC=C(OCO3)C3=C2)[C@H]1CC4=CC=C(OCO5)C5=C4

For research use only. We do not sell to patients.

Summary

Hinokinin (Compound 1) is a compound isolated from the stems of Hypoestes aristate . Hinokinin exhibits moderate activity of HIV-1 protease enzyme ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 282.21 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8221 mL	14.1103 mL	28.2207 mL
5 mM	0.5644 mL	2.8221 mL	5.6441 mL
10 mM	0.2822 mL	1.4110 mL	2.8221 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Ramabulana T, et al. Bioactive Lignans from Hypoestes aristata. J Nat Prod. 2020;83(8):2483-2489.

Synonyms

2(3H)-Furanone, 3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro-, (3R,4R)-

Hinokinin

2(3H)-Furanone, 3,4-bis(1,3-benzodioxol-5-ylmethyl)dihydro-, (3R-trans)-

2(3H)-Furanone, dihydro-3,4-dipiperonyl-, trans-(-)-

(3R,4R)-3,4-Bis(1,3-benzodioxol-5-ylmethyl)dihydro-2(3H)-furanone

Cubebinolide

(-)-Hinokinin

Dihydroisohibalactone

Hinoquinin