[CAS NO. 287174-32-7]  Hydroxy-PEG1-CH2-Boc

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PRODUCTS SPECIFICATIONS [287174-32-7]

Distributor
Catalog
AS259978
Brand
Arctom Scientific
CAS
287174-32-7

DESCRIPTION [287174-32-7]

Overview

MDLMFCD27635155
Molecular Weight176.21
Molecular FormulaC8H16O4
SMILESO=C(OC(C)(C)C)COCCO

For research use only. We do not sell to patients.

Summary

Hydroxy-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1] .


IC50 & Target

PEGs

Alkyl/ether


In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month