[CAS NO. 292843-75-5]  Biotin-PEG2-C2-iodoacetamide

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PRODUCTS SPECIFICATIONS [292843-75-5]

Distributor
Catalog
AS937590
Brand
Arctom Scientific
CAS
292843-75-5

DESCRIPTION [292843-75-5]

Overview

MDL-
Molecular Weight542.43
Molecular FormulaC18H31IN4O5S
SMILESO=C(NCCOCCOCCNC(CI)=O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

For research use only. We do not sell to patients.

Summary

Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1] .


IC50 & Target

PEGs


In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)