[CAS NO. 33068-19-8] 2-Deoxy-D-glucose6-phosphatedisodium
PRODUCTS SPECIFICATIONS [33068-19-8]
DESCRIPTION [33068-19-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 288.10 |
| Molecular Formula | C6H11Na2O8P |
| SMILES | O=P(O[Na])(O[Na])OC[C@@H](O)[C@@H](O)[C@H](O)CC=O |
Summary
2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase [1] .
Appearance
Oil
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H 2 O : 250 mg/mL ( 867.75 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.4710 mL | 17.3551 mL | 34.7102 mL |
| 5 mM | 0.6942 mL | 3.4710 mL | 6.9420 mL |
| 10 mM | 0.3471 mL | 1.7355 mL | 3.4710 mL |
References
- [1] Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.
- [2] B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234.
Synonyms
