[CAS NO. 339-72-0] L-Cycloserine
PRODUCTS SPECIFICATIONS [339-72-0]
DESCRIPTION [339-72-0]
Overview
| MDL | MFCD00064324 |
|---|---|
| Molecular Weight | 102.09 |
| Molecular Formula | C3H6N2O2 |
| SMILES | O=C1NOC[C@@H]1N |
Summary
L-Cycloserine ((S)-4-Amino-3-isoxazolidone) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminitransferase in E. coli, as well in the brains of various animals in a time-dependent manner, results in increased levels of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter in vivo.
Appearance
Solid
Source
Erwinia uredovora.
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
H 2 O : 13.33 mg/mL ( 130.57 mM ; Need ultrasonic)
DMSO : 12.5 mg/mL ( 122.44 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 9.7953 mL | 48.9764 mL | 97.9528 mL |
| 5 mM | 1.9591 mL | 9.7953 mL | 19.5906 mL |
| 10 mM | 0.9795 mL | 4.8976 mL | 9.7953 mL |
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1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (979.53 mM); Clear solution; Need ultrasonic
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2.
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3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 1.25 mg/mL (12.24 mM); Clear solution
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4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 1.25 mg/mL (12.24 mM); Clear solution
Synonyms
