[CAS NO. 40093-94-5]  Torcitabine

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PRODUCTS SPECIFICATIONS [40093-94-5]

Distributor
Catalog
AS060081
Brand
Arctom Scientific
CAS
40093-94-5

DESCRIPTION [40093-94-5]

Overview

MDLMFCD02683609
Molecular Weight227.22
Molecular FormulaC9H13N3O4
SMILESOC[C@H]1[C@H](O)C[C@@H](N2C=CC(N)=NC2=O)O1

For research use only. We do not sell to patients.

Summary

Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine has the potential for chronic hepatitis B virus infection treatment [1] [2] .


In Vitro

Torcitabine (2'-Deoxy-L-cytidine) shows greater inhibition of first strand than second strand DNA synthesis [2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

H 2 O : 250 mg/mL ( 1100.26 mM ; Need ultrasonic)

DMSO : 250 mg/mL ( 1100.26 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4010 mL 22.0051 mL 44.0102 mL
5 mM 0.8802 mL 4.4010 mL 8.8020 mL
10 mM 0.4401 mL 2.2005 mL 4.4010 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (9.15 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (9.15 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (9.15 mM); Clear solution

* All of the co-solvents are available by MCE.