[CAS NO. 406211-06-1]  IKK-IN-1

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PRODUCTS SPECIFICATIONS [406211-06-1]

Store
Catalog
AS904666
Brand
Arctom Scientific
CAS
406211-06-1

DESCRIPTION [406211-06-1]

Overview

MDL-
Molecular Weight431.91
Molecular FormulaC22H26ClN3O4
SMILESO=C1NC2=C(CO1)C(C3CCNCC3)=CC(C(C(O)=CC=C4)=C4OCC5CC5)=N2.Cl

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

IKK-IN-1 is an inhibitor of IKK extracted from patent WO2002024679A1, compound example 18-13.


IC50 & Target

IKK


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)


Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL ( 77.17 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3153 mL 11.5765 mL 23.1530 mL
5 mM 0.4631 mL 2.3153 mL 4.6306 mL
10 mM 0.2315 mL 1.1576 mL 2.3153 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (5.79 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.79 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.79 mM); Clear solution

* All of the co-solvents are available by MCE.