[CAS NO. 41024-91-3] Pentaethylene glycol di(p-toluenesulfonate)

Name: Pentaethylene glycol di(p-toluenesulfonate)
Brand: Arctom Scientific
SKU: AS017470

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [41024-91-3]

Distributor

Catalog

AS017470

Brand

Arctom Scientific

CAS

41024-91-3

DESCRIPTION [41024-91-3]

Overview

MDL	MFCD00012204
Molecular Weight	546.65
Molecular Formula	C24H34O10S2
SMILES	CC1=CC=C(S(=O)(OCCOCCOCCOCCOCCOS(C2=CC=C(C)C=C2)(=O)=O)=O)C=C1

For research use only. We do not sell to patients.

Summary

Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs ^[1] .

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid-liquid mixture

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

References

[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.