[CAS NO. 42079-78-7] 5-methoxyflavone
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PRODUCTS SPECIFICATIONS [42079-78-7]
Distributor
Catalog
AS030821
Brand
Arctom Scientific
CAS
42079-78-7
DESCRIPTION [42079-78-7]
Overview
| MDL | MFCD00016942 |
|---|---|
| Molecular Weight | 252.26 |
| Molecular Formula | C16H12O3 |
| SMILES | O(C)C1=C2C(OC(=CC2=O)C3=CC=CC=C3)=CC=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.9642 mL | 19.8208 mL | 39.6416 mL |
| 5 mM | 0.7928 mL | 3.9642 mL | 7.9283 mL |
| 10 mM | 0.3964 mL | 1.9821 mL | 3.9642 mL |
| 50 mM | 0.0793 mL | 0.3964 mL | 0.7928 mL |
Description
5-methoxyflavone is a novel inhibitor and neuroprotective agent against beta-amyloid toxicity.
Targets
| DNA polymerase β [1] |
In vitro
The treatment with 5-methoxyflavone (5-MF） at various times (3, 6, 12, 18 and 24 h) in MOLT-4 cells results in a time dependent reduction in the levels of antiapoptotic proteins cFLIP, Mcl-1 and an increase in the proapoptotic protein BAX. 5-MF induces both TRAIL-R1(DR4) and TRAIL-R2 (DR5) in a time-dependent manner.
Synonyms
4H-1-Benzopyran-4-one, 5-methoxy-2-phenyl-
Flavone, 5-methoxy-
5-Methoxy-2-phenyl-4H-1-benzopyran-4-one
5-Methoxyflavone
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