[CAS NO. 4712-12-3]  4'-Methylchrysoeriol

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PRODUCTS SPECIFICATIONS [4712-12-3]

Distributor
Catalog
AS953604
Brand
Arctom Scientific
CAS
4712-12-3

DESCRIPTION [4712-12-3]

Overview

MDL-
Molecular Weight314.29
Molecular FormulaC17H14O6
SMILESO=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=CC(O)=C13

For research use only. We do not sell to patients.

Summary

4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC 50 of 19 nM for human P450 1B1-dependent EROD.


IC50 & Target

IC50: 19 nM ( human P450 1B1-dependent EROD) [1] .


In Vitro

4'-Methylchrysoeriol (34DM57DHF) is a potent inhibitor of P450 enzymes, particularly for P450 1B1, with an IC 50 of 19 nM for human P450 1B1-dependent EROD [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 20.83 mg/mL ( 66.28 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1818 mL 15.9089 mL 31.8177 mL
5 mM 0.6364 mL 3.1818 mL 6.3635 mL
10 mM 0.3182 mL 1.5909 mL 3.1818 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.08 mg/mL (6.62 mM); Suspended solution; Need ultrasonic

* All of the co-solvents are available by MCE.