[CAS NO. 4754-39-6] 5'-Deoxyadenosine

Name: 5'-Deoxyadenosine
Brand: Arctom Scientific
SKU: AS267524

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PRODUCTS SPECIFICATIONS [4754-39-6]

Distributor

Catalog

AS267524

Brand

Arctom Scientific

CAS

4754-39-6

DESCRIPTION [4754-39-6]

Overview

MDL	MFCD00056003
Molecular Weight	251.24
Molecular Formula	C10H13N5O3
SMILES	C[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3N)O1)O)O

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Front Cardiovasc Med. 2022 Nov 16;9:1042852.

Summary

5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. 5'-Deoxyadenosine shows anti-orthopoxvirus activity ^[1] .

IC50 & Target

Human Endogenous Metabolite

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 497.53 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9803 mL	19.9013 mL	39.8026 mL
5 mM	0.7961 mL	3.9803 mL	7.9605 mL
10 mM	0.3980 mL	1.9901 mL	3.9803 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (8.28 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (8.28 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (8.28 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.

Synonyms

Adenosine, 5′-deoxy-

5′-Deoxyadenosine