[CAS NO. 4884-68-8] Hydrastinine hydrochloride
PRODUCTS SPECIFICATIONS [4884-68-8]
DESCRIPTION [4884-68-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 243.69 |
| Molecular Formula | C11H14ClNO3 |
| SMILES | OC1N(C)CCC2=C1C=C(OCO3)C3=C2.[H]Cl |
Summary
Hydrastinine hydrochloride is a major alkaloid constituent in goldenseal ( Hydrastis canadensis ). Hydrastinine hydrochloride can be used as a haemostatic agent [1] .
In Vitro
Goldenseal has been used for the treatment of a wide variety of ailments including gastrointestinal disturbances, urinary tract disorders, and inflammation. The five major alkaloid constituents in goldenseal are Berberine, Palmatine, Hydrastine, Hydrastinine, and Canadine [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 83.33 mg/mL ( 341.95 mM ; Need ultrasonic)
H 2 O : 50 mg/mL ( 205.18 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.1036 mL | 20.5179 mL | 41.0357 mL |
| 5 mM | 0.8207 mL | 4.1036 mL | 8.2071 mL |
| 10 mM | 0.4104 mL | 2.0518 mL | 4.1036 mL |
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1.
Add each solvent one by one: PBS
Solubility: 10 mg/mL (41.04 mM); Clear solution; Need ultrasonic
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (8.54 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.08 mg/mL (8.54 mM); Clear solution
References
Synonyms
