[CAS NO. 5041-67-8] Juglanin

Name: Juglanin
Brand: Arctom Scientific
SKU: AS474050

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PRODUCTS SPECIFICATIONS [5041-67-8]

Distributor

Catalog

AS474050

Brand

Arctom Scientific

CAS

5041-67-8

DESCRIPTION [5041-67-8]

Overview

MDL	MFCD26406180
Molecular Weight	418.35
Molecular Formula	C20H18O10
SMILES	O=C1C(O[C@@H]2O[C@@H](CO)[C@H](O)[C@H]2O)=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C41

For research use only. We do not sell to patients.

4 Publications Citing Use of MCE

Summary

Juglanin, a natural occurring flavonoid, is a JNK acticator, with inflammation and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells ^[1] .

IC50 & Target

JNK

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 239.03 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3903 mL	11.9517 mL	23.9034 mL
5 mM	0.4781 mL	2.3903 mL	4.7807 mL
10 mM	0.2390 mL	1.1952 mL	2.3903 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Sun ZL, et al. Juglanin induces apoptosis and autophagy in human breast cancer progression via ROS/JNK promotion. Biomed Pharmacother. 2017 Jan;85:303-312.

Synonyms

4H-1-Benzopyran-4-one, 3-(α-L-arabinofuranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-

Flavone, 3,4′,5,7-tetrahydroxy-, 3-α-L-arabinofuranoside

Juglanin

Arabinofuranoside, kaempferol-3, α-L-

Arabinofuranoside, 5,7-dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl, α-L-

3-(α-L-Arabinofuranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

5,7,4′-Trihydroxyflavone 3-α-L-arabinofuranoside

Euglanin

Juglanin (Juglans)

Kaempferol 3-arabinoside

Kaempferol 3-O-arabinoside

Kaempferol 3-O-α-L-arabinofuranoside