[CAS NO. 50906-56-4]  Arteannuin B

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PRODUCTS SPECIFICATIONS [50906-56-4]

Catalog
HY-N2016
Brand
MCE
CAS
50906-56-4

DESCRIPTION [50906-56-4]

Overview

MDLMFCD09859140
Molecular Weight248.32
Molecular FormulaC15H20O3
SMILESC[C@@]1(CC[C@]2([H])[C@@]3(OC4=O)[C@](CC[C@H]2C)([H])C4=C)[C@H]3O1

For research use only. We do not sell to patients.


Summary

Arteannuin B co-occurs with artemisinin, which is the potent antimalarial principle of the Chinese medicinal herb Artemisia annua (Asteraceae) [1] . Arteannuin B shows anti-SARS-CoV-2 potential with an EC 50 of 10.28 μM [2] .


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 100.68 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0271 mL 20.1353 mL 40.2706 mL
5 mM 0.8054 mL 4.0271 mL 8.0541 mL
10 mM 0.4027 mL 2.0135 mL 4.0271 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 1 mg/mL (4.03 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1 mg/mL (4.03 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 1 mg/mL (4.03 mM); Clear solution

* All of the co-solvents are available by MCE.