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[CAS NO. 517-44-2] Sennidin B
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-N6935 |
| Brand: | MCE |
| CAS: | 517-44-2 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 538.46 |
| Molecular Formula | C30H18O10 |
| SMILES | O=C1C2=C(O)C=C(C(O)=O)C=C2[C@@]([C@]3([H])C4=CC(C(O)=O)=CC(O)=C4C(C5=C(O)C=CC=C35)=O)([H])C6=CC=CC(O)=C16 |
Summary
Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia , has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase , with an IC 50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation [1] [2] .
IC50 & Target
|
GLUT4
|
HCV NS3
|
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL ( 92.86 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.8571 mL | 9.2857 mL | 18.5715 mL |
| 5 mM | 0.3714 mL | 1.8571 mL | 3.7143 mL |
| 10 mM | 0.1857 mL | 0.9286 mL | 1.8571 mL |
References
Synonyms
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