[CAS NO. 53350-26-8] 3',4',5',5,7-Pentamethoxyflavone

Name: 3',4',5',5,7-Pentamethoxyflavone
Brand: Arctom Scientific
SKU: AS010392

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PRODUCTS SPECIFICATIONS [53350-26-8]

Distributor

Catalog

AS010392

Brand

Arctom Scientific

CAS

53350-26-8

DESCRIPTION [53350-26-8]

Overview

MDL	-
Molecular Weight	372.37
Molecular Formula	C20H20O7
SMILES	O=C1C=C(C2=CC(OC)=C(OC)C(OC)=C2)OC3=CC(OC)=CC(OC)=C13

For research use only. We do not sell to patients.

Summary

3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants , sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 67.14 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6855 mL	13.4275 mL	26.8550 mL
5 mM	0.5371 mL	2.6855 mL	5.3710 mL
10 mM	0.2686 mL	1.3428 mL	2.6855 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] Hou X, et al. 3',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway. Mol Cells. 2015 May;38(5):396-401.

Synonyms

4H-1-Benzopyran-4-one, 5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-

Flavone, 3′,4′,5,5′,7-pentamethoxy-

5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one

3′,4′,5,5′,7-Pentamethoxyflavone

Tricetin pentamethyl ether

3′,4′,5′,5,7-Pentamethoxyflavone

5,7,3′,4′,5′-Pentamethoxyflavone

[CAS NO. 53350-26-8] 3',​4',​5',​5,​7-​Pentamethoxyflavone