[CAS NO. 53370-90-4] Exalamide

Name: Exalamide
Brand: Arctom Scientific
SKU: AS459307

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PRODUCTS SPECIFICATIONS [53370-90-4]

Distributor

Catalog

AS459307

Brand

Arctom Scientific

CAS

53370-90-4

DESCRIPTION [53370-90-4]

Overview

MDL	MFCD00865621
Molecular Weight	221.30
Molecular Formula	C13H19NO2
SMILES	O=C(N)C1=CC=CC=C1OCCCCCC

For research use only. We do not sell to patients.

Summary

Exalamide (2-(Hexyloxy)benzamide), an arenecarboxamide, is a potent antifungal agent ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 451.88 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.5188 mL	22.5938 mL	45.1875 mL
5 mM	0.9038 mL	4.5188 mL	9.0375 mL
10 mM	0.4519 mL	2.2594 mL	4.5188 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (11.30 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (11.30 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (11.30 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] T Kusunoki, et al. Comparison of the in vitro antifungal activities of clotrimazole, miconazole, econazole and exalamide against clinical isolates of dermatophytes. J Dermatol. 1984 Jun;11(3):277-81.

Synonyms

Benzamide, 2-(hexyloxy)-

Benzamide, o-(hexyloxy)-

2-(Hexyloxy)benzamide

o-(Hexyloxy)benzamide

2-n-Hexyloxybenzamide

Exalamide

Hyperan

HBA

2-Hexoxybenzamide