[CAS NO. 54680-12-5]  2'-Deoxyadenosine-5'-triphosphatetrisodium

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PRODUCTS SPECIFICATIONS [54680-12-5]

Distributor
Catalog
AS298331
Brand
Arctom Scientific
CAS
54680-12-5

DESCRIPTION [54680-12-5]

Overview

MDLMFCD11164415
Molecular Weight557.13
Molecular FormulaC10H13N5Na3O12P3
SMILESO[C@H]([C@H](O1)CO[P](O[P](O[P](O)(O[Na])=O)(O[Na])=O)(O[Na])=O)C[C@@H]1N2C3=NC=NC(N)=C3N=C2

For research use only. We do not sell to patients.

Summary

2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase [1] .


IC50 & Target

Human Endogenous Metabolite


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT02457052 University Hospital, Toulouse
Deglutition Disorders
October 2014 Not Applicable

Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)


Solvent & Solubility

In Vitro:

H 2 O : 250 mg/mL ( 448.73 mM ; Need ultrasonic)

DMSO : 4.55 mg/mL ( 8.17 mM ; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7949 mL 8.9746 mL 17.9491 mL
5 mM 0.3590 mL 1.7949 mL 3.5898 mL
10 mM 0.1795 mL 0.8975 mL 1.7949 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 100 mg/mL (179.49 mM); Clear solution; Need ultrasonic

* All of the co-solvents are available by MCE.