[CAS NO. 548-61-8] Tris(4-aminophenyl)methane
PRODUCTS SPECIFICATIONS [548-61-8]
DESCRIPTION [548-61-8]
Overview
| MDL | MFCD00137820 |
|---|---|
| Molecular Weight | 289.37 |
| Molecular Formula | C19H19N3 |
| SMILES | NC1=CC=C(C(C2=CC=C(N)C=C2)C3=CC=C(N)C=C3)C=C1 |
Summary
Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.
IC50 & Target
HCV helicase [1]
In Vitro
Tris(4-aminophenyl)methane (Compound 8) shows weak HCV helicase inhibition (30% inhibition at 100 μM) [1] . To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e.g., methyl green, crystal violet, pararosaniline, or Tris(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL ( 172.79 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.4558 mL | 17.2789 mL | 34.5578 mL |
| 5 mM | 0.6912 mL | 3.4558 mL | 6.9116 mL |
| 10 mM | 0.3456 mL | 1.7279 mL | 3.4558 mL |
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1.
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2.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (8.64 mM); Clear solution
Synonyms