[CAS NO. 55028-72-3] Cloprostenol sodium salt

Name: Cloprostenol sodium salt
Brand: Arctom Scientific
SKU: AS940262

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PRODUCTS SPECIFICATIONS [55028-72-3]

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Catalog

AS940262

Brand

Arctom Scientific

CAS

55028-72-3

DESCRIPTION [55028-72-3]

Overview

MDL	-
Molecular Weight	446.90
Molecular Formula	C22H28ClNaO6
SMILES	O=C(O[Na])CCC/C=C\C[C@H]1[C@H](/C=C/[C@H](O)COC2=CC=CC(Cl)=C2)[C@@H](O)C[C@H]1O

For research use only. We do not sell to patients.

Summary

Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent ^[1] , and is a PGF2α receptor agonist ^[2] .

IC50 & Target

PGF2α receptor ^[2]

In Vitro

Cloprostenol is a PGF2α receptor agonist ^[2] .
Cloprostenol (0.1 μM) counteracts the adipogenic effects of statil, on both intracellular lipid accumulation and expression of transcripts for proadipogenic factors C/EBPα and PPARγ after treatment for 6 days ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cloprostenol sodium salt (25 μg) decreases plasma progesterone in pregnant rats ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H ₂ O : ≥ 150 mg/mL ( 335.65 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2376 mL	11.1882 mL	22.3764 mL
5 mM	0.4475 mL	2.2376 mL	4.4753 mL
10 mM	0.2238 mL	1.1188 mL	2.2376 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: PBS

Solubility: 100 mg/mL (223.76 mM); Clear solution; Need ultrasonic

* All of the co-solvents are available by MCE.

References

Synonyms

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, sodium salt (1:1), (5Z)-rel-

5-Heptenoic acid, 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-, monosodium salt, [1α(Z),2β(1E,3R*),3α,5α]-(±)-

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-, monosodium salt, (5Z)-rel-

Cloprostenol sodium salt

Estrumate

ICI 80996

5-Heptenoic acid, 7-[2-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-, monosodium salt, [1α(Z),2β(1E,3R*),3α,5α]-

Estrumat

Planate

Ciosin

Vetmate