[CAS NO. 5581-42-0]  Glyparamide

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PRODUCTS SPECIFICATIONS [5581-42-0]

Distributor
Catalog
AS363723
Brand
Arctom Scientific
CAS
5581-42-0

DESCRIPTION [5581-42-0]

Overview

MDLMFCD00865487
Molecular Weight353.82
Molecular FormulaC15H16ClN3O3S
SMILESO=S(C1=CC=C(Cl)C=C1)(NC(NC2=CC=C(N(C)C)C=C2)=O)=O

For research use only. We do not sell to patients.

Summary

Glyparamide is an orally active chlorophenyl-containing sulfonylurea. Glyparamide shows hypoglycemic activity and rarely causes hepatic injury [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 55 mg/mL ( 155.45 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8263 mL 14.1315 mL 28.2630 mL
5 mM 0.5653 mL 2.8263 mL 5.6526 mL
10 mM 0.2826 mL 1.4131 mL 2.8263 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.75 mg/mL (7.77 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.75 mg/mL (7.77 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.75 mg/mL (7.77 mM); Clear solution

* All of the co-solvents are available by MCE.