[CAS NO. 56100-42-6]  l-Atabrinedihydrochloride

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PRODUCTS SPECIFICATIONS [56100-42-6]

Fulfillment
Catalog
AS903658
Brand
Arctom Scientific
CAS
56100-42-6

DESCRIPTION [56100-42-6]

Overview

MDL-
Molecular Weight472.88
Molecular FormulaC23H32Cl3N3O
SMILESC[C@@H](NC1=C(C=C(OC)C=C2)C2=NC3=CC(Cl)=CC=C31)CCCN(CC)CC.Cl.Cl

For research use only. We do not sell to patients.

Summary

l-Atabrine dihydrochloride is a less active enantiomer of quinacrine which displays antiprion activity.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)


Solvent & Solubility

In Vitro:

H 2 O : 50 mg/mL ( 105.74 mM ; Need ultrasonic)

DMSO : 20 mg/mL ( 42.29 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1147 mL 10.5735 mL 21.1470 mL
5 mM 0.4229 mL 2.1147 mL 4.2294 mL
10 mM 0.2115 mL 1.0574 mL 2.1147 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2 mg/mL (4.23 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2 mg/mL (4.23 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2 mg/mL (4.23 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, dihydrochloride, (R)-
l-Atabrine dihydrochloride