[CAS NO. 564476-33-1] Thiol-PEG4-Boc

Name: Thiol-PEG4-Boc
Brand: Arctom Scientific
SKU: AS031540

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [564476-33-1]

Distributor

Catalog

AS031540

Brand

Arctom Scientific

CAS

564476-33-1

DESCRIPTION [564476-33-1]

Overview

MDL	MFCD11041133
Molecular Weight	338.46
Molecular Formula	C15H30O6S
SMILES	O=C(OC(C)(C)C)CCOCCOCCOCCOCCS

For research use only. We do not sell to patients.

Summary

Thiol-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs ^[1] .

IC50 & Target

PEGs	Alkyl/ether

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Liquid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Synonyms

4,7,10,13-Tetraoxapentadecanoic acid, 15-mercapto-, 1,1-dimethylethyl ester

3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-mercapto-, 1,1-dimethylethyl ester

1,1-Dimethylethyl 15-mercapto-4,7,10,13-tetraoxapentadecanoate

15-Mercapto-4,7,10,13-tetraoxapentadecanoic acid 1,1-dimethylethyl ester