[CAS NO. 5993-18-0]  (±)-Decursinol

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PRODUCTS SPECIFICATIONS [5993-18-0]

Distributor
Catalog
AS952260
Brand
Arctom Scientific
CAS
5993-18-0

DESCRIPTION [5993-18-0]

Overview

MDL-
Molecular Weight246.26
Molecular FormulaC14H14O4
SMILESO=C(O1)C=CC(C1=C2)=CC3=C2OC(C)(C)C(O)C3

For research use only. We do not sell to patients.

Summary

(±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC 50 of 102 μM [1] .


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 406.07 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0607 mL 20.3037 mL 40.6075 mL
5 mM 0.8121 mL 4.0607 mL 8.1215 mL
10 mM 0.4061 mL 2.0304 mL 4.0607 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (10.15 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.15 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.27 mg/mL (1.10 mM); Clear solution

* All of the co-solvents are available by MCE.