[CAS NO. 614726-85-1] CB1antagonist2
PRODUCTS SPECIFICATIONS [614726-85-1]
DESCRIPTION [614726-85-1]
Overview
| MDL | MFCD30537551 |
|---|---|
| Molecular Weight | 380.66 |
| Molecular Formula | C17H12Cl3N3O |
| SMILES | O=C(N)C1=NN(C(C2=CC=C(C=C2)Cl)=C1C)C3=CC=C(C=C3Cl)Cl |
Summary
CB1 antagonist 2 is caimabinoid 1 ( CB1 ) antagonist extracted from patent WO2016184310A1, compound 3, inhibits CB1 in vivo with an IC 50 of 25.5 nM [1] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 62.5 mg/mL ( 164.19 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.6270 mL | 13.1351 mL | 26.2702 mL |
| 5 mM | 0.5254 mL | 2.6270 mL | 5.2540 mL |
| 10 mM | 0.2627 mL | 1.3135 mL | 2.6270 mL |
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1.
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2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.08 mg/mL (5.46 mM); Clear solution
References
