[CAS NO. 6272-55-5] 7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol

Name: 7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol
Brand: Arctom Scientific
SKU: AS684158

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PRODUCTS SPECIFICATIONS [6272-55-5]

Distributor

Catalog

AS684158

Brand

Arctom Scientific

CAS

6272-55-5

DESCRIPTION [6272-55-5]

Overview

MDL	MFCD00192475
Molecular Weight	272.34
Molecular Formula	C20H16O
SMILES	OC1CCCC2=C3C=CC4=CC=CC5=C4C3=C(C=C21)C=C5

For research use only. We do not sell to patients.

Summary

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters ^[1] , which are capable of forming covalent DNA adducts and inducing mutations ^[2] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 917.97 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6719 mL	18.3594 mL	36.7188 mL
5 mM	0.7344 mL	3.6719 mL	7.3438 mL
10 mM	0.3672 mL	1.8359 mL	3.6719 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (7.64 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.08 mg/mL (7.64 mM); Suspended solution; Need ultrasonic

* All of the co-solvents are available by MCE.

References

Synonyms

Benzo[a]pyren-7-ol, 7,8,9,10-tetrahydro-

7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol

7-Hydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene

(RS)-7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol

(±)-7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol

NSC 30871