[CAS NO. 6665-83-4] 6-Hydroxyflavone (6-HF)
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PRODUCTS SPECIFICATIONS [6665-83-4]
Store
Catalog
AS540775
Brand
Arctom Scientific
CAS
6665-83-4
DESCRIPTION [6665-83-4]
Overview
| MDL | MFCD00017329 |
|---|---|
| Molecular Weight | 238.24 |
| Molecular Formula | C15H10O3 |
| SMILES | O=C1C=2C(OC(=C1)C3=CC=CC=C3)=CC=C(O)C2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.1974 mL | 20.9872 mL | 41.9745 mL |
| 5 mM | 0.8395 mL | 4.1974 mL | 8.3949 mL |
| 10 mM | 0.4197 mL | 2.0987 mL | 4.1974 mL |
| 50 mM | 0.0839 mL | 0.4197 mL | 0.8395 mL |
Description
6-Hydroxyflavone, a naturally occurring flavonoid, binds to with moderate affinity and acts as a partial agonist of .
Targets
| GABAA receptor [1] |
In vitro
6HF binds to GABAA receptors with moderate affinity.
In vivo
In mice, 6HF exhibits anxiolytic-like effect in the elevated plus-maze test, unaccompanied at anxiolytic doses by the sedative, cognitive impairing, myorelaxant, motor incoordination and anticonvulsant effects commonly associated with classical BZs when tested in the hole-board, step-through passive avoidance, horizontal wire, rotarod, and pentylenetetrazol (PTZ)-induced seizure tests, respectively.
Synonyms
4H-1-Benzopyran-4-one, 6-hydroxy-2-phenyl-
Flavone, 6-hydroxy-
6-Hydroxy-2-phenyl-4H-1-benzopyran-4-one
6-Hydroxyflavone
NSC 26744
6-Hydroxy-2-phenyl-4H-chromen-4-one
6-Flavonol
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