[CAS NO. 68573-24-0] N-(p-Coumaroyl)Serotonin
PRODUCTS SPECIFICATIONS [68573-24-0]
DESCRIPTION [68573-24-0]
Overview
| MDL | MFCD09840280 |
|---|---|
| Molecular Weight | 322.36 |
| Molecular Formula | C19H18N2O3 |
| SMILES | O=C(NCCC1=CNC2=C1C=C(O)C=C2)/C=C/C3=CC=C(O)C=C3 |
Summary
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca 2+ release from sarcoplasmic reticulum [1] . N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research [2] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 250 mg/mL ( 775.53 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.1021 mL | 15.5106 mL | 31.0212 mL |
| 5 mM | 0.6204 mL | 3.1021 mL | 6.2042 mL |
| 10 mM | 0.3102 mL | 1.5511 mL | 3.1021 mL |
References
- [1] Tetsuya Takimoto, et al. Effect of N-(p-coumaroyl)serotonin and N-feruloylserotonin, major anti-atherogenic polyphenols in safflower seed, on vasodilation, proliferation and migration of vascular smooth muscle cells. Mol Nutr Food Res. 2011 Oct;55(10):156
- [2] Shin-ichiro Katsuda, et al. Safflower seed polyphenols (N-(p-coumaroyl)serotonin and N-feruloylserotonin) ameliorate atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.Hypertens Res
Synonyms
