[CAS NO. 7218-43-1]  Propargyl-PEG2-OH

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PRODUCTS SPECIFICATIONS [7218-43-1]

Distributor
Catalog
AS540274
Brand
Arctom Scientific
CAS
7218-43-1

DESCRIPTION [7218-43-1]

Overview

MDLMFCD00053353
Molecular Weight144.17
Molecular FormulaC7H12O3
SMILESC#CCOCCOCCO

For research use only. We do not sell to patients.

Summary

Propargyl-PEG2-OH is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458) [1] .


IC50 & Target

PEGs


In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Oil


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

Ethanol : ≥ 100 mg/mL ( 693.63 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9363 mL 34.6813 mL 69.3626 mL
5 mM 1.3873 mL 6.9363 mL 13.8725 mL
10 mM 0.6936 mL 3.4681 mL 6.9363 mL
* Please refer to the solubility information to select the appropriate solvent.


Synonyms

Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-
Ethanol, 2-[2-(2-propynyloxy)ethoxy]-
2-[2-(2-Propyn-1-yloxy)ethoxy]ethanol
Diethylene glycol monopropargyl ether
3,6-Dioxa-8-nonyn-1-ol
SR3-062
2-(2-(Prop-2-ynyloxy)ethoxy)ethanol
2-(2-Prop-2-ynoxyethoxy)ethanol