[CAS NO. 72401-54-8]  6-Methoxydihydrosanguinarine

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PRODUCTS SPECIFICATIONS [72401-54-8]

Distributor
Catalog
AS939225
Brand
Arctom Scientific
CAS
72401-54-8

DESCRIPTION [72401-54-8]

Overview

MDL-
Molecular Weight363.36
Molecular FormulaC21H17NO5
SMILESCN1C2=C3C(C=C4OCOC4=C3)=CC=C2C5=C(C6=C(OCO6)C=C5)C1OC

For research use only. We do not sell to patients.

Summary

6-Methoxydihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata . 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC 50 values of 0.61 μM and 0.54 μM, respectively [1] .


IC50 & Target

IC50: 0.61 μM (MCF-7 cells)
IC50: 0.54 μM (SF-268 cells) [1]


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)


Solvent & Solubility

In Vitro:

DMSO : 12.5 mg/mL ( 34.40 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7521 mL 13.7605 mL 27.5209 mL
5 mM 0.5504 mL 2.7521 mL 5.5042 mL
10 mM 0.2752 mL 1.3760 mL 2.7521 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 3.85 mg/mL (10.60 mM); Clear solution

* All of the co-solvents are available by MCE.