[CAS NO. 77307-50-7] SL0101-1

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [77307-50-7]

Catalog

HY-15237

Brand

MCE

CAS

77307-50-7

DESCRIPTION [77307-50-7]

Overview

MDL	MFCD09842349
Molecular Weight	516.45
Molecular Formula	C25H24O12
SMILES	OC1=CC(O)=C(C(C(O[C@@H]2O[C@@H](C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]2O)=C(C3=CC=C(O)C=C3)O4)=O)C4=C1

For research use only. We do not sell to patients.

3 Publications Citing Use of MCE

Summary

SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta , is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC ₅₀ of 89 nM ^[1] . SL 0101-1 (SL0101) is a selective RSK1/2 inhibitor, with a K _i of 1 μM ^[2] .

IC50 & Target

RSK1

In Vitro

SL 0101-1 (SL0101) shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G ₁ phase ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

References

Synonyms

4H-1-Benzopyran-4-one, 3-[(3,4-di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-

3-[(3,4-Di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

3′′,4′′-Di-O-acetylafzelin

Kaempferol 3-O-(3′′,4′′-di-O-acetyl-α-L-rhamnopyranoside)

SL 0101-1

SL 0101