[CAS NO. 7803-88-5] 6-O-Methyl Guanosine

Name: 6-O-Methyl Guanosine
Brand: Arctom Scientific
SKU: AS209262

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PRODUCTS SPECIFICATIONS [7803-88-5]

Distributor

Catalog

AS209262

Brand

Arctom Scientific

CAS

7803-88-5

DESCRIPTION [7803-88-5]

Overview

MDL	MFCD01723912
Molecular Weight	297.27
Molecular Formula	C11H15N5O5
SMILES	OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=C(N)N=C3OC)O1)O)O

For research use only. We do not sell to patients.

Summary

6-O-Methyl Guanosine is a modified nucleoside ^[1] . 6-O-Methyl Guanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line ^[2] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 130 mg/mL ( 437.31 mM ; Need ultrasonic)

H ₂ O : 2 mg/mL ( 6.73 mM ; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3639 mL	16.8197 mL	33.6395 mL
5 mM	0.6728 mL	3.3639 mL	6.7279 mL
10 mM	0.3364 mL	1.6820 mL	3.3639 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 6.5 mg/mL (21.87 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 6.5 mg/mL (21.87 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 6.5 mg/mL (21.87 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

Guanosine, 6-O-methyl-

9H-Purine, 2-amino-6-methoxy-9-β-D-ribofuranosyl-

6-O-Methylguanosine

2-Amino-6-methoxypurine ribonucleoside

6-Methoxy-9-β-D-ribofuranosyl-9H-purin-2-amine

O-Methylguanosine

O⁶-Methylguanosine

NSC 66381

6-Methylguanosine