[CAS NO. 80755-51-7]  Bunazosin

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [80755-51-7]

Catalog
AS483725
Brand
Arctom Scientific
CAS
80755-51-7

DESCRIPTION [80755-51-7]

Overview

MDLMFCD00865793
Molecular Weight373.45
Molecular FormulaC19H27N5O3
SMILESNC1=NC(N2CCN(C(CCC)=O)CCC2)=NC3=CC(OC)=C(OC)C=C13

For research use only. We do not sell to patients.

Summary

Bunazosin is a potent and selective α1-adrenoceptor antagonist. Bunazosin can be used for antihypertensive and ocular hypotensive research [1] .


IC50 & Target

α1-adrenergic receptor


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT00130156 Eisai Inc.|Eisai Co., Ltd.
High Blood Pressure
October 2005 Phase 4

Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 267.77 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6777 mL 13.3887 mL 26.7773 mL
5 mM 0.5355 mL 2.6777 mL 5.3555 mL
10 mM 0.2678 mL 1.3389 mL 2.6777 mL
* Please refer to the solubility information to select the appropriate solvent.


Synonyms

1-Butanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-1H-1,4-diazepin-1-yl]-
1H-1,4-Diazepine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-4-(1-oxobutyl)-
1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-1H-1,4-diazepin-1-yl]-1-butanone
Bunazosin
E 1015
1-[4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-1,4-diazepan-1-yl]butan-1-one