[CAS NO. 80971-60-4] n-Butyl-β-D-fructofuranoside
PRODUCTS SPECIFICATIONS [80971-60-4]
DESCRIPTION [80971-60-4]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 236.26 |
| Molecular Formula | C10H20O6 |
| SMILES | CCCCO[C@](O[C@@H]1CO)([C@H]([C@@H]1O)O)CO |
Summary
IC50 & Target
|
Bax |
Bcl-2 |
In Vitro
n-Butyl-β-D-fructofuranoside (0-23.6 μg/mL; 24-78 hours) has antiproliferation activity and inhibits the viability of Bel-7402 cells
[1]
.
n-Butyl-β-D-fructofuranoside (0-75 μg/mL; 0-72 hours) inhibits BEL-7402 cells by interfering with cell cycle and inducing apoptosis
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay [1]
| Cell Line: | Bel-7402 cells |
| Concentration: | 0.47, 2.95, 5.90, 11.8, 17.7 and 23.6 μg/mL |
| Incubation Time: | 24, 48 and 72 hours |
| Result: | Inhibited the proliferation of Bel-7402 cells at both time- and dose-dependent manner. |
Cell Cycle Analysis [1]
| Cell Line: | Bel-7402 cells |
| Concentration: | 0, 50 and 75 μg/mL |
| Incubation Time: | 24, 48 and 72 hours |
| Result: | Induced cell cycle arrest at G0/G1 phase. |
Western Blot Analysis [1]
| Cell Line: | Bel-7402 cells |
| Concentration: | 23.6 μg/mL |
| Incubation Time: | 0, 24, 48 and 72 hours |
| Result: | Decreased Bcl-2 and increased Bax and p53 levels in a time manner. |
Appearance
Oil
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL ( 423.26 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.2326 mL | 21.1631 mL | 42.3263 mL |
| 5 mM | 0.8465 mL | 4.2326 mL | 8.4653 mL |
| 10 mM | 0.4233 mL | 2.1163 mL | 4.2326 mL |