[CAS NO. 831217-40-4] MAL3-101

Name: MAL3-101
Brand: Arctom Scientific
SKU: AS931434

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PRODUCTS SPECIFICATIONS [831217-40-4]

Distributor

Catalog

AS931434

Brand

Arctom Scientific

CAS

831217-40-4

DESCRIPTION [831217-40-4]

Overview

MDL	-
Molecular Weight	931.12
Molecular Formula	C54H66N4O10
SMILES	O=C(C1=C(C)N(CCCCCC(N(C(C2=CC=C(OCC(OC)=O)C(C(OC)=O)=C2)C(NCCCC)=O)CCCCCC)=O)C(NC1C3=CC=CC=C3C4=CC=CC=C4)=O)OCC5=CC=CC=C5

For research use only. We do not sell to patients.

Summary

MAL3-101 is a potent HSP70 allosteric inhibitor. MAL3-101 inhibits HSP70 ATPase activity by blocking Hsp40 co-chaperone interaction. MAL3-101 can be used for researching muscle invasive bladder cancer (MIBC) ^[1] .

IC50 & Target

HSP70

In Vitro

MAL3-101 (10 μM; 24, 48, 72 hours) induces cell viability in MIBC cell lines UMUC3, T24, SW780 and J82 ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

References

[1] Prince T, et al. Dual targeting of HSP70 does not induce the heat shock response and synergistically reduces cell viability in muscle invasive bladder cancer. Oncotarget. 2018 Aug 24;9(66):32702-32717.