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[CAS NO. 87239-81-4] Cefpodoxime Proxetil
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-N7101 |
| Brand: | MCE |
| CAS: | 87239-81-4 |
Overview
| MDL | MFCD00865088 |
|---|---|
| Molecular Weight | 557.60 |
| Molecular Formula | C21H27N5O9S2 |
| SMILES | O=C(C(N12)=C(COC)CS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)OC(OC(OC(C)C)=O)C |
Summary
Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin. Cefpodoxime Proxetil binds to penicillin binding proteins ( PBPs ), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis [1] .
IC50 & Target
|
β-lactam
|
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT03491748 | Entasis Therapeutics |
Healthy Volunteers
|
March 16, 2018 | Phase 1 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 125 mg/mL ( 224.18 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.7934 mL | 8.9670 mL | 17.9340 mL |
| 5 mM | 0.3587 mL | 1.7934 mL | 3.5868 mL |
| 10 mM | 0.1793 mL | 0.8967 mL | 1.7934 mL |
Synonyms
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