[CAS NO. 97-67-6]  (S)-Malic acid

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [97-67-6]

Distributor
Catalog
HY-Y1069
Brand
MCE
CAS
97-67-6

DESCRIPTION [97-67-6]

Overview

MDLMFCD00064213
Molecular Weight134.09
Molecular FormulaC4H6O5
SMILESO=C(O)[C@@H](O)CC(O)=O

For research use only. We do not sell to patients.

Summary

(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.


IC50 & Target

Human Endogenous Metabolite


In Vitro

It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L. casei . Furthermore, deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid, thus indicating that the cognate TC system regulates and is essential for the expression of ME. Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose, whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

H 2 O : 100 mg/mL ( 745.77 mM ; Need ultrasonic)

DMSO : 100 mg/mL ( 745.77 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.4577 mL 37.2884 mL 74.5768 mL
5 mM 1.4915 mL 7.4577 mL 14.9154 mL
10 mM 0.7458 mL 3.7288 mL 7.4577 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (18.64 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (18.64 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (18.64 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Butanedioic acid, 2-hydroxy-, (2S)-
Malic acid, L-
Butanedioic acid, hydroxy-, (S)-
Butanedioic acid, hydroxy-, (2S)-
Malic acid, l-
(2S)-2-Hydroxybutanedioic acid
Apple acid
(-)-Hydroxysuccinic acid
(-)-Malic acid
L-Malic acid
L-(-)-Malic acid
(S)-Malic acid
S-(-)-Malic acid
(-)-(S)-Malic acid
S-2-Hydroxybutanedioic acid
(-)-L-Malic acid
NSC 9232
(2S)-2-Hydroxysuccinic acid
L-Apple acid
(2S)-Malic acid
(S)-2-Hydroxysuccinic acid
(2S)-2-Hydroxysuccinic acid
(2S)-2-Hydroxybutanedioic acid