[CAS NO. 1241046-32-1] QM295
PRODUCTS SPECIFICATIONS [1241046-32-1]
DESCRIPTION [1241046-32-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 295.29 |
| Molecular Formula | C17H13NO4 |
| SMILES | O=C1C(/C=C2C=CC(C(OC)=C/2)=O)=C(C3=CC=CC=C3)NO1 |
Summary
QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress [1] .
In Vitro
QM295 (25 μM, 50 μM) inhibits the development of AUR fluorescence in a kinetic assay with an IC 50 value of 1.9 μM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
QM295 (50 μM, 30 min) has the accumulation of an ERO1α form with lower mobility in vivo [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)