[CAS NO. 503860-52-4] Shishijimicin C
PRODUCTS SPECIFICATIONS [503860-52-4]
DESCRIPTION [503860-52-4]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 967.16 |
| Molecular Formula | C45H50N4O12S4 |
| SMILES | O=C(C1=C(NC2=CC=C3O)C(C2=C3)=CC=N1)[C@@]([C@@H]([C@H]4O[C@H](OC[C@@H]5NCC)C[C@@H]5OC)O)([C@H](O[C@H]4O[C@@H](C#C/C=C\C#C[C@@]6(C7)O)C(/C6=C\CSSSC)=C(C7=O)NC(OC)=O)C)SC |
Summary
Shishijimicin C is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin C shows anti-tumor activity with highly potent cytotoxicities [1] .
In Vitro
Shishijimicin C (compound 3) (1.7-6.3 pg/mL) shows high cytotoxicity for 3Y1, Hela and P388 cells [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Cytotoxicity Assay [1]
| Cell Line: | 3Y1, Hela and P388 cells |
| Concentration: | 1.7-6.3 pg/mL |
| Incubation Time: | |
| Result: | Showed IC 50 values of 4.8, 6.3, and 1.7 pg/mL for 3Y1, Hela and P388 cells, respectively. |
Source
Didemnum proliferum
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
