[CAS NO. 79127-35-8] Echinosporin
PRODUCTS SPECIFICATIONS [79127-35-8]
DESCRIPTION [79127-35-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 223.18 |
| Molecular Formula | C10H9NO5 |
| SMILES | O=C(C1=C[C@@]([C@@](C(O2)=O)(O)C=C3)([H])[C@@]3([H])[C@@]2([H])O1)N |
Summary
Echinosporin (XK-213) is an antibiotic . Echinosporin can be isolated from Amycolatopsis strain. Echinosporin has antifungal activity and antitumor activity [1] [2] .
IC50 & Target
MIC50: 64 μg/mL ( Fusarium oxysporum ); 64 μg/mL ( Fusarium solani ); 32 μg/mL ( Alternaria panax ); 64 μg/mL ( Phoma herbarum ) [2] .
In Vitro
Echinosporin (XK-213) exhibits weak antibacterial activities against Gram-positive and -negative microorganisms and its shows antitumor activity
[1]
.
Echinosporin exhibits antifungal activity against root-rot pathogens of Panax notoginseng include
Fusarium oxysporum
,
Fusarium solani
,
Alternaria panax
, and
Phoma herbarum
with the MIC
50
value at 64, 64, 32, and 64 μg/mL, respectively
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Source
streptomyces echinosporus MK-213
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
References
- [1] T Sato, et al. A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterization. J Antibiot (Tokyo). 1982 Mar;35(3):266-71.
- [2] Xindong Xu, et al. Echinosporin antibiotics isolated from Amycolatopsis strain and their antifungal activity against root-rot pathogens of the Panax notoginseng. Folia Microbiol (Praha). 2019 Mar;64(2):171-175.