[CAS NO. 912789-08-3] ISX-3
PRODUCTS SPECIFICATIONS [912789-08-3]
DESCRIPTION [912789-08-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 330.77 |
| Molecular Formula | C16H15ClN4O2 |
| SMILES | O=C(C1=NOC(C2=CC(Cl)=CC=C2)=C1)NCCCN3C=NC=C3 |
Summary
In Vitro
ISX-3 (0-100,000 nM; 10 days) shows a stimulatory effect on the accumulation of lipid droplets and an inhibitory effect on ALP (alkaline phosphatase) induction
[1]
.
ISX-3 (50 µM; 2 days) increases the expression of PPARγ in the presence of MDI in hBMSCs
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Western Blot Analysis [1]
| Cell Line: | hBMSCs |
| Concentration: | 50 µM |
| Incubation Time: | 2 days |
| Result: | Increased the PPARγ expression level in the presence of MDI (0.5 mM isobutyl methylxanthine, 1 μM dexamethasone and 1 μM insulin). |
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.