[CAS NO. 2353409-80-8] Gly-Gly-Gly-PEG4-DBCO
PRODUCTS SPECIFICATIONS [2353409-80-8]
DESCRIPTION [2353409-80-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 694.77 |
| Molecular Formula | C35H46N6O9 |
| SMILES | O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCOCCNC(CNC(CNC(CN)=O)=O)=O)=O |
Summary
Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1] .
IC50 & Target
|
Cleavable |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
Methanol : 50 mg/mL ( 71.97 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.4393 mL | 7.1966 mL | 14.3933 mL |
| 5 mM | 0.2879 mL | 1.4393 mL | 2.8787 mL |
| 10 mM | 0.1439 mL | 0.7197 mL | 1.4393 mL |