[CAS NO. 2395887-69-9] Mal-PEG2-VCP-NB

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PRODUCTS SPECIFICATIONS [2395887-69-9]

Catalog

AS1137310

Brand

Arctom Scientific

CAS

2395887-69-9

MDL	-
Molecular Weight	783.78
Molecular Formula	C36H45N7O13
SMILES	O=C(OCC1=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCN2C(C=CC2=O)=O)=O)=O)=O)C=C1)OC3=CC=C([N+]([O-])=O)C=C3

For research use only. We do not sell to patients.

Mal-PEG2-VCP-NB is a claevable ADC linker containing a Maleimide group, 2-unit PEG and a VCP NB.

Protease Cleavable

Cleavable

Solid

Room temperature in continental US; may vary elsewhere.

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

In Vitro:

DMSO : 100 mg/mL ( 127.59 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.67 mg/mL (3.41 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.67 mg/mL (3.41 mM); Suspended solution; Need ultrasonic
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.67 mg/mL (3.41 mM); Clear solution

* All of the co-solvents are available by MCE.