| MDL | MFCD26960951 |
|---|---|
| Molecular Weight | 964.26 |
| Molecular Formula | C51H77N7O9S |
| SMILES | O=C1N(CCCCCC(N(C)[C@H](C(N[C@@H](C(C)C)C(N(C)[C@]([C@@H](C)CC)([H])[C@@H](CC(N2[C@H]([C@H](OC)[C@H](C(N[C@@H](CC3=CC=CC=C3)C4=NC=CS4)=O)C)CCC2)=O)OC)=O)=O)C(C)C)=O)C(C=C1)=O |
Mc-MMAD is a protective group (maleimidocaproyl)-conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a drug-linker conjugate for ADC.
|
Auristatin |
Solid
Room temperature in continental US; may vary elsewhere.
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years |
* The compound is unstable in solutions, freshly prepared is recommended.
DMSO : ≥ 100 mg/mL ( 103.71 mM )
* "≥" means soluble, but saturation unknown.
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.0371 mL | 5.1853 mL | 10.3706 mL |
| 5 mM | 0.2074 mL | 1.0371 mL | 2.0741 mL |
| 10 mM | 0.1037 mL | 0.5185 mL | 1.0371 mL |
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (2.59 mM); Clear solution