[CAS NO. 126766-32-3] GR 89696

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PRODUCTS SPECIFICATIONS [126766-32-3]

Catalog

AS951407

Brand

Arctom Scientific

CAS

126766-32-3

DESCRIPTION [126766-32-3]

Overview

MDL	-
Molecular Weight	530.40
Molecular Formula	C23H29Cl2N3O7
SMILES	OC(/C=C/C(O)=O)=O.ClC(C=C1CC(N2C(CN(CC2)C(OC)=O)CN3CCCC3)=O)=C(C=C1)Cl

For research use only. We do not sell to patients.

Summary

GR 89696 is a highly selective κ2 opioid receptor agonist with potential to prevent pruritus ^[1] .

In Vivo

GR 89696 (intramuscular injection, 0.01-0.1 μg/kg) attenuates the scratching response induced by intrathecal morphine (0.03mg) in a dose-dependent manner without affecting the analgesic effect of morphine ^[1] .
GR-896960(subcutaneous injection, 1 mg/kg) reduces cerebral artery infarct volume by 38% in a rat model of permanent focal ischemia ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

Synonyms

1-Piperazinecarboxylic acid, 4-[2-(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)

1-Piperazinecarboxylic acid, 4-[(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (E)-2-butenedioate (1:1)

1-Piperazinecarboxylic acid, 4-[(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)

GR 89696