[CAS NO. 125-15-5] Vomicine

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PRODUCTS SPECIFICATIONS [125-15-5]

Catalog

AS960799

Brand

Arctom Scientific

CAS

125-15-5

DESCRIPTION [125-15-5]

Overview

MDL	-
Molecular Weight	380.44
Molecular Formula	C22H24N2O4
SMILES	O=C1[C@@]23[C@](N4C5=C(O)C=CC=C35)([H])[C@@]6([H])[C@@](C(CN(C)CC2)=CCO[C@@]6([H])CC4=O)([H])C1

For research use only. We do not sell to patients.

Summary

Vomicine, an alkaloid, shows antidiabetic activity ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL ( 26.29 mM ; ultrasonic and warming and heat to 60°C)

H ₂ O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6285 mL	13.1427 mL	26.2854 mL
5 mM	0.5257 mL	2.6285 mL	5.2571 mL
10 mM	0.2629 mL	1.3143 mL	2.6285 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 1 mg/mL (2.63 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1 mg/mL (2.63 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 1 mg/mL (2.63 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Bhati R, et al. seeds: Pharmacognostical standardization, extraction, and antidiabetic activity. J Ayurveda Integr Med. 2012 Apr;3(2):80-4.

Synonyms

12H-6a,4-(Ethaniminomethano)indolo[3,2,1-ij]oxepino[2,3,4-de]quinoline-6,12(2H)-dione, 4a,5,13,13a,13b,13c-hexahydro-10-hydroxy-16-methyl-, (4aR,6aS,13aS,13bR,13cS)-

Vomicine

16,19-Secostrychnidine-10,16-dione, 4-hydroxy-19-methyl-

(4aR,6aS,13aS,13bR,13cS)-4a,5,13,13a,13b,13c-Hexahydro-10-hydroxy-16-methyl-12H-6a,4-(ethaniminomethano)indolo[3,2,1-ij]oxepino[2,3,4-de]quinoline-6,12(2H)-dione

Vomicin

Strychnicine

12H-6a,4-(Ethaniminomethano)indolo[3,2,1-ij]oxepino[2,3,4-de]quinoline-6,12(2H)-dione, 4a,5,13,13a,13b,13c-hexahydro-10-hydroxy-16-methyl-, [4aR-(4aR*,6aS*,13aS*,13bR*,13cS*)]-

12-Hydroxyicajine