[CAS NO. 1353546-86-7] Orismilast

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PRODUCTS SPECIFICATIONS [1353546-86-7]

Catalog

AS963239

Brand

Arctom Scientific

CAS

1353546-86-7

MDL	-
Molecular Weight	510.29
Molecular Formula	C19H15Cl2F2NO7S
SMILES	O=S1(CCC2(OC3=C(C=CC(C(CC4=C(C=[N+](C=C4Cl)[O-])Cl)=O)=C3O2)OC(F)F)CC1)=O

For research use only. We do not sell to patients.

Orismilast (LEO-32731) is a PDE4 inhibitor used for the research of inflammatory diseases ^[1] .

NCT Number	Sponsor	Condition	Start Date	Phase
NCT05469464	UNION therapeutics	Atopic Dermatitis\|Skin Diseases	July 11, 2022	Phase 2
NCT05190419	UNION therapeutics	Psoriasis\|Skin Diseases	December 30, 2021	Phase 2
NCT04982432	Gregor Jemec\|UNION therapeutics\|Zealand University Hospital	Hidradenitis Suppurativa	October 1, 2021	Phase 2
NCT05490316	Innovent Biologics (Suzhou) Co. Ltd.	Healthy Subjects	September 1, 2022	Phase 1

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 100 mg/mL ( 195.97 mM ; Need ultrasonic)

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Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.