[CAS NO. 1357349-91-7]  SPP-86

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PRODUCTS SPECIFICATIONS [1357349-91-7]

Catalog
AS963405
Brand
Arctom Scientific
CAS
1357349-91-7

DESCRIPTION [1357349-91-7]

Overview

MDL-
Molecular Weight277.32
Molecular FormulaC16H15N5
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.6059 mL18.0297 mL36.0594 mL
5 mM0.7212 mL3.6059 mL7.2119 mL
10 mM0.3606 mL1.8030 mL3.6059 mL
50 mM0.0721 mL0.3606 mL0.7212 mL

Description

SPP-86, a potent and selective cell permeable inhibitor of with an IC50 of 8 nM, inhibits RET-induced and signaling, also inhibits RET-induced phosphorylation in MCF7 cells.

Targets

PI3K [1]Akt [1]ERα [1]