[CAS NO. 137173-46-7]  N-dodecanoyl-L-Homoserinelactone

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PRODUCTS SPECIFICATIONS [137173-46-7]

Catalog
AS963740
Brand
Arctom Scientific
CAS
137173-46-7

DESCRIPTION [137173-46-7]

Overview

MDL-
Molecular Weight283.41
Molecular FormulaC16H29NO3
SMILESCCCCCCCCCCCC(N[C@H]1CCOC1=O)=O

For research use only. We do not sell to patients.

Summary

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa [1] .


In Vitro

Disruption of cell-cell communication or quorum sensing (QS) is considered a stimulating approach for reducing bacterial pathogenicity and resistance [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 88.21 mM ; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5285 mL 17.6423 mL 35.2846 mL
5 mM 0.7057 mL 3.5285 mL 7.0569 mL
10 mM 0.3528 mL 1.7642 mL 3.5285 mL
* Please refer to the solubility information to select the appropriate solvent.


Synonyms

Dodecanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
Dodecanamide, N-(tetrahydro-2-oxo-3-furanyl)-, (S)-
N-[(3S)-Tetrahydro-2-oxo-3-furanyl]dodecanamide
N-Dodecanoyl-L-homoserine lactone
C12-HSL (autoinducer)
(S)-N-(2-Oxotetrahydrofuran-3-yl)dodecanamide