[CAS NO. 160434-48-0] 4-Desmethyl Istradefylline

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PRODUCTS SPECIFICATIONS [160434-48-0]

Catalog

AS967317

Brand

Arctom Scientific

CAS

160434-48-0

DESCRIPTION [160434-48-0]

Overview

MDL	-
Molecular Weight	370.40
Molecular Formula	C19H22N4O4
SMILES	O=C(N1CC)N(CC)C2=C(N(C)C(/C=C/C3=CC=C(O)C(OC)=C3)=N2)C1=O

For research use only. We do not sell to patients.

Summary

4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with K _i of 2.2 nM in experimental models of Parkinson's disease ^[1] .

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Chen JF, et al. Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease. J Neurosci. 2001 May 15;21(10):RC143.